Frederic Derbre

Voici une sélection de mes publications scientifiques récentes.

Couvert A, Lacaze L, Touboulic S, Gautier S, Guérin S, Randuineau G, Romé V, Malbert CH, Val-Laillet D, Derbré F, Thibault R. The Yucatan minipig model: a new preclinical model of malnutrition in obese patients with acute or chronic diseases.Clin Nutr. 2023 Dec15. Online ahead of print.

Robin F, Chappard D, Leroyer P, Latour C, Mabilleau G, Monbet V, Cavey T, Horeau M, Derbré F, Roth M-P, Ropert M,Guggenbuhl P, Loréal O. Differences in bone microarchitecture between genetic and secondary iron‐overload mouse models suggest a role for hepcidin deficiency in iron‐related osteoporosis. FASEB. 2023 Nov;37(11):e23245. doi: 10.1096/fj.202301184R.

Lacaze L, Rochdi S, Couvert A, Touboulic S, Guérin S, Randuineau G, Martin D, Romé V, Malbert CH, Derbré F, Val-Laillet D, Thibault R. The Yucatan minipig model: A new preclinical model of malnutrition induced by a low-calorie/low-protein diet. Clin Nutr. 2022 Aug 10;41(10):2077-2086. doi: 10.1016/j.clnu.2022.08.002. Online ahead of print.

Horeau M, Ropert M, Mulder E, Tank J, Frings-Meuthen P, Armbrecht G, Loréal O, Derbré F. Iron Metabolism Regulation in Females and Males Exposed to Simulated Microgravity: results from the Randomized Trial AGBRESA. Am J Clin Nutr. 2022 Aug 26:nqac205. doi: 10.1093/ajcn/nqac205. Online ahead of print.

Martin D, Nay K, Robin F, Rebillard A, Orfila L, Martin B, Leroyer P, Guggenbuhl P, Dufresne S, Noirez P, Ropert M, Loréal O, Derbré F. Oxidative and glycolytic skeletal muscles deploy protective mechanisms to avoid atrophy under pathophysiological iron overload.   J Cachexia Sarcopenia Muscle. 2022 Feb 3. doi: 10.1002/jcsm.12897. Online ahead of print.

Jollet M, Nay K, Chopard A, Bareille MP, Beck A, Ollendorff V, Vernus B, Bonnieu A, Mariadassou M, Rué O, Derbré F, Goustard B, Koechlin-Ramonatxo C. Nutrients.  Does Physical Inactivity Induce Significant Changes in Human Gut Microbiota? New Answers Using the Dry Immersion Hypoactivity Model. Nutrients. 2021 Oct 29;13(11):3865. doi: 10.3390/nu13113865

Nay K, Horeau M, Loréal O, Derbré F. Métabolisme du fer : impact de l’hypoactivité et mécanismes sous-jacents. Cahiers de nutrition et diététique. 2021. 52(2) : 132-440.

Nay K, Koechlin-Ramonatxo C, Rochdi S, Island ML, Orfila L, Treffel L, Bareille MP, Beck A, Gauquelin-Koch G, Ropert M, Loréal O, , Derbré F. Simulated microgravity disturbs iron metabolism and distribution in humans: lessons from dry immersion, an innovative ground-based human model. FASEB 2020 Sep 12 [Epub ahead of print]

Nay K, Martin D, Orfila L, Saligaut D, Martin B, Horeau M, Cavey T, Kenawi M, Island ML, Ropert M, Loréal O, Koechlin-Ramonatxo C, Derbré F. Intermittent reloading does not prevent iron availability decrease and hepcidin upregulation caused by hindlimb unloading. Exp Physiol 2020 Apr 13. [Epub ahead of print]

Kenawi M, Rouger E, Island ML, Leroyer P, Robin F, Remy S, Anegon I, Nay K, Derbré F, Brissot P, Ropert M, Cavey T, Loréal O. Ceruloplasmin deficiency does not induce macrophagic iron overload: lessons from a new rat model of hereditary aceruloplasminemia. FASEB. 2019 Aug 26. [Epub ahead of print]

Nay K., Jollet M., Goustard B., Baati N., Vernus B., Pontones M., Lefeuvre-Orfila L., Bendavid C., Rué O., Mariadassou M., Bonnieu A. , Ollendorff V., Lepage P., Derbré F., Koechlin-Ramonatxo C. Gut bacteria are critical for optimal muscle function: a potential link with glucose homeostasis. Am J Physiol End Meta. 2019 Jul 1;317(1):E158-E171.

Appriou A., Nay K., Pierre, N., Saligaut D., Lefeuvre-Orfila L., Martin B., Cavey T., Ropert M., Loréal O., Rannou-Bekono F., Derbré F.  Skeletal muscle ceramides do not contribute to physical inactivity-induced insulin resistance. Applied Physiol Nutr and Metab 2019 Mar 19. [Epub ahead of print]

Ferrando B, Gomez-Cabrera MC, Salvador-Pascual A, Puchades C, Derbré F, Gratas-Delamarche A, Laparre L, Olaso-Gonzalez G, Cerda M, Viosca E, Alabajos A, Sebastiá V, Alberich-Bayarri A, García-Castro,  Viña J. Allopurinol  partially prevents disuse muscle atrophy in mice and humans. Sci Reports. 2018 [Epub]

Davies JMS, Cillard J, Friguet B, Cadenas E, Cadet J, Cayce R, Fishmann A, Liao D, Bulteau AL, Derbré F, Rébillard A, Burstein S, Hirsch E, Kloner RA, Jakowec M, Petzinger G, Sauce D, Sennlaub F, Limon I, Ursini F, Maiorino M, Economides C, Pike CJ, Cohen P, Salvayre AN, Halliday MR, Lundquist AJ, Jakowec NA, Mechta-Grigoriou F, Mericskay M, Mariani J, Li Z, Huang D, Grant E, Forman HJ, Finch CE, Sun PY, Pomatto LCD, Agbulut O, Warburton D, Neri C, Rouis M, Cillard P, Capeau J, Rosenbaum J, Davies KJA. The Oxygen Paradox, the French Paradox, and age-related diseases. Geroscience. 2017 Dec;39(5-6):499-550. doi: 10.1007/s11357-017-0002-y. Epub 2017 Dec 21. Review.

Assi M, Derbré F, Lefeuvre-Orfila L, Saligaut D, Stock N, Ropars M, Rébillard A. Maintaining a regular physical activity aggravates intramuscular tumor growth in an orthotopic liposarcoma model. Am J Cancer Res. 2017 May 1;7(5):1037-1053. eCollection 2017.

Cavey T, Pierre N, Nay K, Allain C, Ropert M, Loréal O, Derbré F. Simulated microgravity reduces iron bioavailability in rats: role of inflammation-induced hepcidin upregulation. Exp Physiol. 2017. Mar 1;102(3):291-298